There are three basic types of arthritis that may affect the knee joint. 

Osteoarthritis (OA) is the most common form of knee arthritis. OA is usually a slowly progressive degenerative disease in which the joint cartilage gradually wears away. It most often affects middle-aged and older people.

Rheumatoid Arthritis 
Rheumatoid arthritis (RA) is an inflammatory type of arthritis that can destroy the joint cartilage. RA can occur at any age. RA generally affects both knees.

Post-traumatic Arthritis 
Post-traumatic arthritis can develop after an injury to the knee. This type of knee arthritis is similar to osteoarthritis and may develop years after a fracture, ligament injury, or meniscus tear.

Healthy Knee
Knee Arthritis
A healthy knee
An osteoarthritic knee

Generally, the pain associated with arthritis develops gradually, although sudden onset is also possible. The joint may become stiff and swollen, making it difficult to bend or straighten the knee.

Pain and swelling are worse in the morning or after a period of inactivity. Pain may also increase after activities such as walking, stair climbing, or kneeling.

The pain may often cause a feeling of weakness in the knee, resulting in a “locking” or “buckling.” Many people report that changes in the weather also affect the degree of pain from arthritis.

Doctor Examination 
Your orthopedic doctor will perform a physical examination that focuses on your walk, the range of motion in the limb, and joint swelling or tenderness.

X-rays typically show a loss of joint space in the affected knee.

Blood and other special imaging tests, such as magnetic resonance imaging (MRI) may be needed to diagnose rheumatoid arthritis.

Healthy knee
An osteoarthritic knee
A healthy knee
An osteoarthritic knee

Nonsurgical Treatment 
If you have osteoarthritis of the knee, you can take advantage of a wide range of treatment options. The effectiveness of different treatments varies from person to person. The choice of treatment should be a joint decision between you and your physician.

The purpose of treatment is to reduce pain, increase function and generally reduce your symptoms. Patient satisfaction is a fundamental goal in treating osteoarthritis of the knee

In its early stages, arthritis of the knee is treated with nonsurgical measures. Nonsurgical treatments fall into four major groups: lifestyle modifications; exercise; supportive devices; other methods.

Lifestyle Modification 
Lifestyle modifications can include losing weight, switching from running or jumping exercises to swimming or cycling, and minimizing activities that aggravate the condition, such as climbing stairs. Many, but not all, people with osteoarthritis of the knee are overweight. Simple weight loss can reduce stress on weight bearing joints, such as the knee. Losing weight can result in reduced pain and increased function, particularly in walking.

Exercises can help increase range of motion and flexibility as well as help strengthen the muscles in the leg. Physical therapy and exercise are often effective in reducing pain and improving function. Your physician or a physical therapist can help develop an individualized exercise program that meets your needs and lifestyle

Supportive Devices
Using supportive devices, such as a cane, wearing energy-absorbing shoes or inserts, or wearing a brace or knee sleeve can be helpful. A brace can assist with stability and function. There are two types of braces that are often used. An “unloader” brace shifts load away from the affected portion of the knee. A “support” brace helps support the entire knee load.

Other Methods
Other measures may include applications of heat or ice, water exercises, liniments or elastic bandages.

Drug Treatment 
Several types of drugs can be used in treating knee arthritis. Because every patient is different, and because not all people respond the same to medications, your orthopedic surgeon will develop a program for your specific condition.

Anti-inflammatory medications such as aspirin or ibuprofen may help reduce swelling in the joint. Simple pain relievers such as Tylenol are available without a prescription and can be very effective in reducing pain. Pain relievers are usually the first choice of therapy for osteoarthritis of the knee.

All drugs have potential side effects and simple analgesics are no exception. In addition, with time, your body can build up a tolerance, reducing the effects of the pain reliever. It is important to realize that these medications, although purchased over-the-counter, can also interact with other medications you are taking, such as blood-thinners. Be sure to discuss these issues with your doctor.

Glucosamine and Chondroitin
Glucosamine and chondroitin (kon-dro’-i-tin) sulfate are oral supplements may relieve the pain of osteoarthritis. These are two molecules that are found in the cartilage of our joints. Supplements sold over-the-counter are usually made from synthetic or animal products.

Glucosamine and/or chondroitin sulfate may be particularly helpful in the early stages of osteoarthritis of the knee, provided they are used as directed on package inserts and with caution. Although glucosamine and chondroitin sulfate are natural substances, sometimes classified as food additives, they can cause side effects such as headaches, stomach upset, nausea, vomiting, and skin reactions. These supplements can interact with other medications, so keep Dr Samimiinformed about your use of them.

These substances can help reduce swelling and tenderness, as well as improve mobility and function. If you decide to take this therapy, it is important not to discontinue too soon. At least two months of continuous use is necessary before the full effect is realized.

Corticosteroids are powerful anti-inflammatory agents that can be injected into the joint. They are given for moderate to severe pain. They can be very useful if there is significant swelling, but are not very helpful if the arthritis affects the joint mechanics.

Corticosteroids are natural substances known as hormones. They are produced by the adrenal glands in the human body. They can provide pain relief and reduce inflammation with a subsequent increase in quadriceps (thigh muscle) strength. However, the effects are not long-lasting, and no more than four injections should be given per joint per year.

In addition, there is some concern about the use of these injections. For example, pain and swelling may “flare” immediately after the injection, and the potential exists for long-term joint damage or infection. With frequent repeated injections or over an extended period of time, joint damage can actually increase rather than decrease.

Viscosupplementation with Hyaluronic Acid
A relatively new procedure, called viscosupplementation, injects a preparation of hyaluronic acid into the knee joint. Hyaluronic acid is a naturally occurring substance found in the synovial (joint) fluid. It acts as a lubricant to enable bones to move smoothly over each other and as a shock absorber for joint loads.

People with osteoarthritis (“wear-and-tear” arthritis) have a lower-than-normal concentration of hyaluronic acid in their joints. Viscosupplementation may be a therapeutic option for individuals with osteoarthritis of the knee.

Surgical Treatment
If your knee arthritis does not respond to these nonsurgical treatments, you may need to have knee surgery. There are a number of surgical options, including the following:

Arthroscopic Surgery:
Arthroscopic surgery enables your surgeon to see inside the knee joint in order to clean it of debris and remove torn cartilage. Knee arthroscopy is useful in osteoarthritis and most helpful when arthritis is mild.

Knee Replacement:
A total or partial knee arthroplasty replaces the severely damaged knee joint cartilage with metal and plastic.

Knee Arthritis Surgery